Until recently, scientists believed that mature adult cells were permanently locked into their differentiated state and unable to return to their pluripotent stem cell state. BlueRock’s focus is the natural evolution of the discoveries that shattered those old dogmas.
Built on the research of some of the world’s foremost experts in induced pluripotent stem cell (iPSC) biology, BlueRock has revolutionized and scaled methods for creating authentic cell types in the areas of neurology, cardiology, and immunology.
What is cell+gene?
BlueRock has developed an exquisite and powerful platform, cell+gene, that reprograms mature, differentiated cells back to iPSC’s and applies advanced engineering to enhance the cells’ therapeutic capabilities. We then use advanced bioprocesses to re-differentiate these iPSCs into new, authentic replacements of cells damaged or lost to disease.
- Cell: highly specific authentic cells, manufactured from iPSCs under rigorous process control
- Gene: genetic engineering to enhance those authentic cells with specific functions to improve their therapeutic effect
The BlueRock Difference – Authentic Cells
BlueRock has a superior understanding and know-how of the intricate requirements needed to differentiate pluripotent cells into specific cells in the body – neuronal cells, cardiac cells, immune cells and more. Using our proprietary bioprocess and manufacturing techniques, we create stable master cell banks capable of virtually unlimited expansion and differentiation into any cell type.
Our advanced gene editing capabilities further allow us to engineer iPSCs into authentic cells to enable new therapeutic modalities. BlueRock scientists can program those replacement cells to carry out specific functions, whether that be delivering lost signals in the brain, pumping blood in the heart, or activating a therapeutic immune response.
Our expertise in producing authentic cells opens the door to creating medicines that raise the standard of care from outdated “band-aid” fixes to replacing cells that have been lost, and engineering them to work seamlessly with the surrounding healthy cells to restore function.
Key Advantages
BlueRock’s expertise in building master cell banks creates endless possibilities for what diseases we can treat – we just need to know the precise recipe to make the cell type we desire. We can grow these cells to high numbers and freeze them down so that they’re readily available when needed and can be quickly scaled to meet industrial needs.